Bringing Scientific Expertise to the VC Market—with Arkady Kulik of RPV

According to a BCG report, only 19% of VCs have some kind of scientific or technological competence. And that creates a translation problem between deep tech founders and investors. </p> </p>To close that gap, Arkady Kulik and his cofounder, Tamaz Khunjua, built <a href="https://rpv.global/index.html">RPV</a>, a venture fund that brings scientific expertise to the market and helps scientists become strong entrepreneurs.</p> </p>On this episode of The Boost VC Podcast, Arkady joins us to explain how the RPV team’s extensive background in science and entrepreneurship serves deep tech startups.</p> </p>Arkady describes how starting a venture fund differs from founding other companies and shares his excitement around ‘being at the edge of science’ as a frontier tech VC.</p> </p>Listen in for Arkady’s unique take on what it means to be useful to others and learn how RPV is working to make talented scientists billionaires!</p> </p><strong>Topics Covered</strong></p> </p>The idea behind RPV</p><ul><li>Help scientists become strong entrepreneurs</li><li>‘Commercialization of science’</li></ul> </p>How Arkady got into venture capital</p><ul><li>Moved to US to be part of scientific exploration of humanity</li><li>Lack of funding in prototyping stage of deep tech startups</li></ul> </p>Arkady’s biggest accomplishment before age 20</p><ul><li>Launched first company at 18 without external investment</li><li>Scaled to annual revenue of $5M in third year</li></ul> </p>How starting a venture fund differs from starting other companies</p><ul><li>More competitive, thousands of similar funds raising money</li><li>Harer to differentiate and properly tell story of niche</li></ul> </p>What part of being a VC Arkady enjoys the most</p><ul><li>Being at edge of science and meeting interesting people</li><li>Finding processes that make things work</li></ul> </p>The secret skills Arkady is most proud of</p><ul><li>Developed extreme level of discipline</li><li>Extremely organized in managing time and data</li></ul> </p>How Arkady thinks about being useful to others</p><ul><li>Provide with relevant information or connections</li><li>Put smile on someone’s face, make life better</li></ul> </p>The most valuable thing RPV provides for deep tech startups</p><ul><li>External proof point for science and technology</li><li>Entrepreneurial experience and change management</li></ul> </p>Arkady’s ‘deathbed test’ to measure success</p><ul><li>Nothing ‘could have but didn’t achieve’</li><li>Self-actualization (happy, complex person)</li></ul> </p><strong>Connect with Arkady Kulik</strong></p> </p>RPV <a href="https://rpv.global/">https://rpv.global/</a></p>RPV on LinkedIn <a href="https://www.linkedin.com/company/rpvglobal/">https://www.linkedin.com/company/rpvglobal/</a></p>Arkady on LinkedIn <a href="https://www.linkedin.com/in/arkady-kulik/">https://www.linkedin.com/in/arkady-kulik/</a></p>Arkady on X <a href="https://twitter.com/arkadykulik">https://twitter.com/arkadykulik</a> </p> </p><strong>Resources</strong></p> </p>Starburst Aerospace <a href="https://starburst.aero/">https://starburst.aero/</a></p>Cantos VC <a href="https://cantos.vc/">https://cantos.vc/</a></p>Countdown <a href="https://countdown.capital/">https://countdown.capital/</a></p>Fifty Years <a href="https://fiftyyears.com/">https://fiftyyears.com/</a></p>Productivity Planner <a href="https://www.intelligentchange.com/products/productivity-planner">https://www.intelligentchange.com/products/productivity-planner</a></p>Terraforming Mars <a href="https://www.fryxgames.se/games/terraforming-mars/">https://www.fryxgames.se/games/terraforming-mars/</a></p><i>Breakfast with Pops: A Venture Capital Handbook</i> by Adam Draper and William H. Draper III <a href="https://www.amazon.com/Breakfast-Pops-Venture-Capital-Handbook/dp/B0C1JHXTQF">https://www.amazon.com/Breakfast-Pops-Venture-Capital-Handbook/dp/B0C1JHXTQF</a></p> </p><strong>Connect with Boost VC</strong></p> </p>Boost VC Website <a href="https://www.boost.vc/">https://www.boost.vc/</a></p>Boost VC on Facebook <a href="https://www.facebook.com/boostvc/">https://www.facebook.com/boostvc/</a></p>Boost VC on X <a href="https://twitter.com/BoostVC">https://twitter.com/BoostVC</a></p>Boost VC on Instagram <a href="https://www.instagram.com/boost_vc/">https://www.instagram.com/boost_vc/</a></p> </p>

00:42:02

DeepTech Series Ep # 4: Betting on Mission-Driven Deep Tech—with Maryanna Saenko of Future Ventures

If a VC is excited about a deep tech company upfront, what can we do to temper our enthusiasm and make a rational decision on whether to invest?</p> </p>Maryanna Saenko is Cofounder and Partner at <a href="https://future.ventures/">Future Ventures</a>, an early-stage VC firm that focuses on mission-driven companies at the cutting edge of disruptive technology.</p> </p>Future Ventures looks to back visionaries who push the boundaries of possibility. Some of their recent investments include Beeflow, Deep Genomics and Earthshot Labs.</p> </p>On this episode of Boost VC, Maryanna joins us to share her definition of deep tech, describing how Future Ventures looks for opportunities ‘unlike anything we’ve ever seen before.’</p> </p>Maryanna offers her take on why the two-person structure of a venture firm is ideal and discusses some of the deep tech deals she wishes she’d been closer to.</p> </p>Listen in for Maryanna’s insight on building organizations around big shifts in science or technology and learn her process for dialing down the excitement after a pitch to decide whether her YES will hold.</p> </p><strong>Topics Covered</strong></p> </p>Maryanna’s biggest accomplishments before age 20</p><ul><li>Recognized she wouldn’t survive public high school</li><li>Got into Hopkins prep school on scholarship</li></ul> </p>How Maryanna got into venture capital</p><ul><li>Worked for early-stage company out of college</li><li>Job offer from Daimler to figure out driverless cars</li><li>Introduced to head of innovation lab at Airbus</li></ul> </p>The most important lessons Maryanna has learned as a VC</p><ul><li>Trust your intuition</li><li>Don’t waste time justifying a startup’s relevance</li></ul> </p>How Maryanna defines deep tech</p><ul><li>‘Unlike anything we’ve ever seen before’</li><li>Index on novelty at Future Ventures</li></ul> </p>What Maryanna does when she’s all-in on a company right away</p><ul><li>Asks what she must believe about reality for YES to hold</li><li>Discussion with partner to temper her excitement</li></ul> </p>Why Maryanna prefers the two-person structure in venture</p><ul><li>Ideal for its efficiency and intellectual honesty</li><li>Never puts someone in tie-breaker position</li></ul> </p>Maryanna’s superpowers as a venture investor</p><ul><li>Confident in ability to assess tech on first principles</li><li>Know how to build orgs around shifts in science or tech </li></ul> </p>What deals Maryanna wishes she had been closer to</p><ul><li>Structure of open AI</li><li>Deep seabed mining, recycling battery technology</li></ul> </p>Maryanna’s definition of success</p><ul><li>Feel landscape of possibility was totally exhausted</li><li>‘Everything I could give to this, I did’</li></ul> </p><strong>Connect with Maryanna Saenko</strong></p> </p>Future Ventures <a href="https://future.ventures/">https://future.ventures/</a> </p>Future on Facebook <a href="https://www.facebook.com/FutureVenturesVC">https://www.facebook.com/FutureVenturesVC</a></p>Future on Instagram <a href="https://www.instagram.com/future.ventures/">https://www.instagram.com/future.ventures/</a></p>Future on LinkedIn <a href="https://www.linkedin.com/company/futureventures/">https://www.linkedin.com/company/futureventures/</a></p>Maryanna on LinkedIn <a href="https://www.linkedin.com/in/maryannasaenko/">https://www.linkedin.com/in/maryannasaenko/</a></p>Maryanna on Twitter <a href="https://twitter.com/FutureSaenko">https://twitter.com/FutureSaenko</a></p> </p><strong>Resources</strong></p> </p>Lux Research <a href="https://www.luxresearchinc.com/">https://www.luxresearchinc.com/</a></p>DARPA Grand Challenge <a href="https://www.darpa.mil/about-us/timeline/-grand-challenge-for-autonomous-vehicles">https://www.darpa.mil/about-us/timeline/-grand-challenge-for-autonomous-vehicles</a></p>Airbus BizLab <a href="https://www.airbus.com/en/innovation/innovation-ecosystem/airbus-bizlab">https://www.airbus.com/en/innovation/innovation-ecosystem/airbus-bizlab</a></p>Beeflow  <a href="https://www.beeflow.com/">https://www.beeflow.com/</a></p><i>Decoding the World</i> by Po Bronson and Arvind Gupta <a href="https://www.amazon.com/Decoding-World-Questioner-Po-Bronson/dp/1538734311">https://www.amazon.com/Decoding-World-Questioner-Po-Bronson/dp/1538734311</a></p>Redwood Materials <a href="https://www.redwoodmaterials.com/">https://www.redwoodmaterials.com/</a></p><i>American Prometheus: The Triumph and Tragedy of J. Robert Oppenheimer </i>by Kai Bird and Martin J. Sherwin <a href="https://www.amazon.com/American-Prometheus-audiobook/dp/B000OZ0J0W/">https://www.amazon.com/American-Prometheus-audiobook/dp/B000OZ0J0W/</a></p> </p><strong>Connect with Boost VC</strong></p> </p>Boost VC Website <a href="https://www.boost.vc/">https://www.boost.vc/</a></p>Boost VC on Facebook <a href="https://www.facebook.com/boostvc/">https://www.facebook.com/boostvc/</a></p>Boost VC on Twitter <a href="https://twitter.com/BoostVC">https://twitter.com/BoostVC</a></p>Boost VC on Instagram <a href="https://www.instagram.com/boost_vc/">https://www.instagram.com/boost_vc/</a></p> </p>

00:50:27

DeepTech Series Ep # 3: What to Look for in a Deep Tech Founder—with Greg Castle of Anorak Ventures

Deep tech founders are either technically gifted or great at building a business. But it's seldom both, at least in the beginning.</p> </p>So, what should venture investors pay attention to when we’re choosing founders in these disruptive technologies?</p> </p>Greg Castle is Founder and Managing Director at <a href="https://www.anorak.vc/">Anorak Ventures</a>, a firm that invests in early-stage deep tech startups.</p> </p>An entrepreneur and corporate marketer turned VC, Greg has invested in 120 companies, including Oculus, Flexport and Mux.</p> </p>On this episode of Boost VC, Greg joins us to explore how his view of venture investing has changed since he wrote his first check, explaining what he looks for in a founder and how he evaluates deep tech startups differently.</p> </p>Greg shares his mixed feelings about the VR market right now and how he benefits from having a partner to engage in conviction-based decision-making.</p> </p>Listen in for Greg’s advice on where to deploy capital in deep tech and learn how Anorak chooses founders who apply disruptive technologies to business problems in any industry.</p> </p><strong>Topics Covered</strong></p> </p>How Greg got into venture capital</p><ul><li>Curious person who advocates for people he believes in</li><li>Got lucky in first few personal investments, e.g.: Oculus</li></ul> </p>The most important lessons Greg has learned as a VC</p><ul><li>What high-functioning teams and companies look like</li><li>Not to take it personally when things don’t go as planned</li></ul> </p>What Greg pays attention to when he’s choosing founders</p><ul><li>How they interact with cofounders, react to feedback</li><li>Punctuality at meetings, preparedness and responsiveness</li></ul> </p>The questions Greg asks himself before he invests in a startup</p><ul><li>Do I believe in the founder?</li><li>Do I believe in the market?</li></ul> </p>How Greg evaluates deep tech companies differently</p><ul><li>Move forward with presumption that anything’s possible</li><li>Consider if technically gifted person can build business</li></ul> </p>Greg’s mixed feelings about the VR market right now</p><ul><li>Viable platform where developers make real money</li><li>Frustrated by lack of competition, Meta fumbling the ball</li></ul> </p>Greg’s thoughts on Apple entering the VR/AR market</p><ul><li>‘Nobody can make a product cool like Apple can’</li><li>Not well-positioned in immersive gaming (primary use case)</li></ul> </p>The Anorak investment thesis</p><ul><li>Handful of technologies will have outsized impact on future</li><li>Find teams leveraging those technologies, industry agnostic</li></ul> </p>Greg’s advice on where to deploy capital in deep tech</p><ul><li>Always comes down to people</li><li>Build out ecosystem of investors, founders</li></ul> </p>How Greg thinks about scale in venture investing</p><ul><li>Find great people in areas that are not your strengths</li><li>Scale of funds = $15M to $25M per partner</li></ul> </p>How Greg benefits from taking on a partner</p><ul><li>Need to explain yourself to thought partner</li><li>Can still move quickly when he needs to</li></ul> </p>Greg’s biggest accomplishments before age 20</p><ul><li>Building group of friends in college</li><li>Still works with many of them</li></ul> </p>Greg’s definition of success</p><ul><li>Confident and comfortable in your own skin</li><li>Content with what you have</li></ul> </p><strong>Connect with Greg Castle</strong></p> </p>Anorak Ventures <a href="https://www.anorak.vc/">https://www.anorak.vc/</a></p>Anorak on Medium <a href="https://anorakvc.medium.com/">https://anorakvc.medium.com/</a></p>Anorak on Twitter <a href="https://twitter.com/AnorakVentures">https://twitter.com/AnorakVentures</a></p>Anorak on LinkedIn <a href="https://www.linkedin.com/company/anorak-ventures/">https://www.linkedin.com/company/anorak-ventures/</a></p>Greg on LinkedIn <a href="https://www.linkedin.com/in/gregorycastle/">https://www.linkedin.com/in/gregorycastle/</a></p>Greg on Twitter <a href="https://twitter.com/gpcastle12">https://twitter.com/gpcastle12</a></p> </p><strong>Resources</strong></p> </p>Greg Castle on Boost VC EP001 <a href="https://www.youtube.com/watch?v=2PyO3LpZD9Q">https://www.youtube.com/watch?v=2PyO3LpZD9Q</a></p>Greg Castle on Boost VC EP089 <a href="https://open.spotify.com/episode/6qYRcDMoemjrMHDxKONu4A">https://open.spotify.com/episode/6qYRcDMoemjrMHDxKONu4A</a></p>Oculus <a href="https://www.meta.com/quest/">https://www.meta.com/quest/</a></p>GOLF+ <a href="https://www.golfplusvr.com/">https://www.golfplusvr.com/</a></p>FitXR <a href="https://fitxr.com/">https://fitxr.com/</a></p><i>Neverwhere </i>by Neil Gaiman <a href="https://www.amazon.com/Neverwhere-Novel-Neil-Gaiman-ebook/dp/B000FC130E">https://www.amazon.com/Neverwhere-Novel-Neil-Gaiman-ebook/dp/B000FC130E</a></p><i>Snow Crash</i> by Neal Stephenson <a href="https://www.amazon.com/Snow-Crash-Novel-Neal-Stephenson-ebook/dp/B000FBJCJE/">https://www.amazon.com/Snow-Crash-Novel-Neal-Stephenson-ebook/dp/B000FBJCJE/</a></p><i>Hyperion</i> by Dan Simmons <a href="https://www.amazon.com/Hyperion-Cantos-Book-1-ebook/dp/B004G60EHS/">https://www.amazon.com/Hyperion-Cantos-Book-1-ebook/dp/B004G60EHS/</a></p><i>Neuromancer</i> by William Gibson <a href="https://www.amazon.com/Neuromancer-Sprawl-Trilogy-William-Gibson-ebook/dp/B000O76ON6/">https://www.amazon.com/Neuromancer-Sprawl-Trilogy-William-Gibson-ebook/dp/B000O76ON6/</a> </p><i>Breakfast with Pops: A Venture Capital Handbook</i> by Adam Draper & William Henry Draper, III <a href="https://www.amazon.com/Breakfast-Pops-Venture-Capital-Handbook/dp/B0C1JHXTQF">https://www.amazon.com/Breakfast-Pops-Venture-Capital-Handbook/dp/B0C1JHXTQF</a></p>‘Perception Is Reality’ Presentation <a href="https://www.anorak.vc/post/perception-is-reality-8-startup-marketing-principles">https://www.anorak.vc/post/perception-is-reality-8-startup-marketing-principles</a></p> </p><strong>Connect with Boost VC</strong></p> </p>Boost VC Website <a href="https://www.boost.vc/">https://www.boost.vc/</a></p>Boost VC on Facebook <a href="https://www.facebook.com/boostvc/">https://www.facebook.com/boostvc/</a></p>Boost VC on Twitter <a href="https://twitter.com/BoostVC">https://twitter.com/BoostVC</a></p>Boost VC on Instagram <a href="https://www.instagram.com/boost_vc/">https://www.instagram.com/boost_vc/</a></p>

00:45:22

DeepTech Series Ep # 2: Thesis Development for Deep Tech—with Seth Winterroth of Eclipse Ventures

How does a venture firm approach investments in deep technology?</p> </p>Seth Winterroth is Partner at <a href="https://eclipse.vc/">Eclipse Ventures</a>, a VC firm that partners with exceptional entrepreneurs to build companies that redefine physical industries.</p> </p>Seth has nine years of experience in venture capital, serving as Associate at GE Ventures before he joined the team at Eclipse. </p> </p>On this episode of Boost VC, Seth joins us to explore how Eclipse thinks about investing in emerging technologies, explaining how the team engages with customers and leverages internal expertise to identify high-magnitude market opportunities. </p> </p>Seth shares his interest in robotics, discussing why the acquisition of Kiva Systems sparked his interest in this particular deep tech field and how he identified the opportunity to invest in 6 River Systems—the first deal he led at Eclipse. </p> </p>Listen in for Seth’s advice to young VCs on cultivating patience and responding to chaos with calm, engaging with founders in a way that’s rational and devoid of fear.</p> </p><strong>Topics Covered</strong></p> </p>The thesis at Eclipse Ventures</p><ul><li>Small teams of engineers solving hard development problems</li><li>Industries that operate in physical world (80% of global GDP)</li></ul> </p>How Seth thinks about investing in emerging technology</p><ul><li>Start with markets, customer pain points</li><li>Find specialist to develop n-of-1 solution</li><li>Add traditional engineers with experience scaling technology</li></ul> </p>What gets Seth excited about robotics</p><ul><li>Kiva Systems acquisition by Amazon sparked interest</li><li>Saw market trends driving adoption of autonomous systems</li></ul> </p>The success of Seth’s first investment at Eclipse, 6 River Systems</p><ul><li>Robotics company in supply chain logistics</li><li>Acquired for $500M by Shopify in 2019</li></ul> </p>How Seth identified the opportunity to invest in 6 River Systems</p><ul><li>Ideal team profile and product differentiation</li><li>Gap in market to replace Kiva Systems</li></ul> </p>Eclipse’s institutional process of thesis development</p><ul><li>Engage with customers, purchasing decision-makers</li><li>Internal engineering expertise to identify gaps</li></ul> </p>Eclipse’s internal venture equity program</p><ul><li>Cases where did research but didn’t find right opportunity </li><li>Engineer storm vs. wait for lightning to strike</li></ul> </p>What Eclipse does to win deals</p><ul><li>Build relationships with founders</li><li>Provide evidence of value-added capital</li></ul> </p>The part of a deal Seth is most excited about</p><ul><li>Find high-magnitude market opportunity to match worldview</li><li>Go to partners with conviction and say THIS ONE</li></ul> </p>What Seth would tell his 25-year-old self</p><ul><li>Be patient, don’t rush to have track record in venture</li><li>Respond to chaos with calm, be rational and devoid of fear</li></ul> </p>What differentiates Eclipse from other venture firms</p><ul><li>Tackle category of economy traditional VCs shy away from</li><li>Deep involvement with companies to improve odds</li></ul> </p>Seth’s biggest accomplishments before age 20</p><ul><li>Live on own and travel world</li><li>Spend meaningful time with and learn from grandfather</li></ul> </p><strong>Connect with Seth Winterroth</strong></p> </p>Eclipse Ventures <a href="https://eclipse.vc/">https://eclipse.vc/</a></p>Eclipse on LinkedIn <a href="https://www.linkedin.com/company/eclipse-vc/">https://www.linkedin.com/company/eclipse-vc/</a></p>Eclipse on Twitter <a href="https://twitter.com/eclipseventures">https://twitter.com/eclipseventures</a> </p>Seth on Twitter <a href="https://twitter.com/Sethwinterroth">https://twitter.com/Sethwinterroth</a></p>Seth on LinkedIn <a href="https://www.linkedin.com/in/sethwinterroth/">https://www.linkedin.com/in/sethwinterroth/</a></p> </p><strong>Resources</strong></p> </p>Kiva Systems Acquisition <a href="https://techcrunch.com/2012/03/19/amazon-acquires-online-fulfillment-company-kiva-systems-for-775-million-in-cash/">https://techcrunch.com/2012/03/19/amazon-acquires-online-fulfillment-company-kiva-systems-for-775-million-in-cash/</a></p>Willow Garage <a href="https://www.businessinsider.com/a-look-back-at-willow-garage-2016-2">https://www.businessinsider.com/a-look-back-at-willow-garage-2016-2</a></p>DARPA Grand Challenge <a href="https://www.darpa.mil/about-us/timeline/-grand-challenge-for-autonomous-vehicles">https://www.darpa.mil/about-us/timeline/-grand-challenge-for-autonomous-vehicles</a></p>6 River Systems <a href="https://6river.com/">https://6river.com/</a></p>Bright Machines <a href="https://www.brightmachines.com/">https://www.brightmachines.com/</a></p>BrightInsight <a href="https://brightinsight.com/">https://brightinsight.com/</a></p>Foxglove Studio <a href="https://foxglove.dev/">https://foxglove.dev/</a></p>Kevin Kelly’s Blog ‘You Are Not Late’ <a href="https://medium.com/message/you-are-not-late-b3d76f963142">https://medium.com/message/you-are-not-late-b3d76f963142</a></p>Richard Hamming’s Talk ‘You and Your Research’ <a href="https://www.youtube.com/watch?v=a1zDuOPkMSw">https://www.youtube.com/watch?v=a1zDuOPkMSw</a></p><i>Team of Rivals: The Political Genius of Abraham Lincoln </i>by Doris Kearns Goodwin <a href="https://www.amazon.com/Team-Rivals-Political-Abraham-Lincoln/dp/0743270754">https://www.amazon.com/Team-Rivals-Political-Abraham-Lincoln/dp/0743270754</a></p><i>Lincoln</i> <a href="https://www.imdb.com/title/tt0443272/">https://www.imdb.com/title/tt0443272/</a></p> </p><strong>Connect with Boost VC</strong></p> </p>Boost VC Website <a href="https://www.boost.vc/">https://www.boost.vc/</a></p>Boost VC on Facebook <a href="https://www.facebook.com/boostvc/">https://www.facebook.com/boostvc/</a></p>Boost VC on Twitter <a href="https://twitter.com/BoostVC">https://twitter.com/BoostVC</a></p>Boost VC on Instagram <a href="https://www.instagram.com/boost_vc/">https://www.instagram.com/boost_vc/</a></p>

00:43:53

DeepTech Series Ep # 1: Making Global-Scale Impact Through Deep Tech—with Ian Rountree of Cantos

What inspires a venture firm to focus on deep tech?</p> </p>Ian Rountree is Founder and General Partner at <a href="https://cantos.vc/">Cantos</a>, a venture fund that invests in potentially world-changing deep tech startups. </p> </p>Cantos focuses on hardware and bio investing at the intersection of climate and industrials, life sciences and AI, aerospace and defense, and next-generation computing.</p> </p>On this episode of Boost VC, Ian joins us to share his definition of deep tech and explain why he underwrites technical risk rather than market risk.</p> </p>Ian discusses the value of founder empathy, challenging VCs to see the entrepreneur as their customer and LPs as shareholders in the portfolio.</p> </p>Listen in to understand what drives Ian to make a global-scale impact, backing founders who tackle climate change, disease, armed conflict, poverty and existential risk.</p> </p><strong>Topics Covered</strong></p> </p>Ian’s biggest accomplishment before age 20</p><ul><li>Getting Vanderbilt to accept him off waitlist </li><li>Refused to take NO as answer</li></ul> </p>Ian’s take on who is the customer in venture capital</p><ul><li>Founder = customer</li><li>LP = shareholder</li></ul> </p>What inspired Ian to focus on deep tech</p><ul><li>Tackle big problems, e.g.: climate change, poverty</li><li>Deep tech startups outperformed rest of portfolio</li></ul> </p>How losing his father early informs Ian’s work</p><ul><li>Feels hard deadline to career and life</li><li>Wants to play small role in changing world</li></ul> </p>The criteria Ian uses to decide if a startup is ‘important’</p><ul><li>Nonzero chance of global-scale impact</li><li>Tackles climate, disease, armed conflict or poverty</li></ul> </p>How Ian defines deep tech</p><ul><li>Taking technical risk rather than market risk</li><li>Cantos specializes in hardware and bio investing</li></ul> </p>How Ian thinks about growing the Cantos organization</p><ul><li>From solo GP to 4 equal partners</li><li>‘Fire’ himself by age 55</li></ul> </p>What’s behind Benchmark’s equal partnership structure</p><ul><li>Set up for generational turnover from jump</li><li>May also be consequence of early success</li></ul> </p>Why a deep tech VC doesn’t need to be technical</p><ul><li>Ask expert if violation of physics involved</li><li>Startups that change world challenge status quo</li></ul> </p>What differentiates software investing from deep tech</p><ul><li>Software involves market risk, easy to pivot</li><li>Deep tech involves technical risk, hard to pivot</li></ul> </p>Ian’s diligence criteria</p><ul><li>Size of market, potential margins at scale</li><li>Founder who understands their WHY</li></ul> </p><strong>Connect with Ian Rountree</strong></p> </p>Cantos <a href="https://cantos.vc/">https://cantos.vc/</a></p>Cantos on Twitter <a href="https://twitter.com/cantos">https://twitter.com/cantos</a></p>Ian on Twitter <a href="https://twitter.com/ianrountree">https://twitter.com/ianrountree</a></p>Ian on LinkedIn    <a href="https://www.linkedin.com/in/ianrountree/">https://www.linkedin.com/in/ianrountree/</a></p>Near Frontier Podcast <a href="https://nearfrontier.castos.com/">https://nearfrontier.castos.com/</a></p> </p><strong>Resources</strong></p> </p>Fred Wilson’s Blog ‘The VC’s Customer’ <a href="https://avc.com/2005/11/the_vcs_custome/">https://avc.com/2005/11/the_vcs_custome/</a></p>Fred Wilson’s Blog ‘The VC’s Customer (Continued)’ <a href="https://avc.com/2009/07/the-vcs-customer-continued/">https://avc.com/2009/07/the-vcs-customer-continued/</a></p>Radiant <a href="https://www.radiantnuclear.com/">https://www.radiantnuclear.com/</a></p>Tim Urban’s TED Talk on Procrastination <a href="https://www.ted.com/talks/tim_urban_inside_the_mind_of_a_master_procrastinator/c">https://www.ted.com/talks/tim_urban_inside_the_mind_of_a_master_procrastinator/c</a></p>Benchmark <a href="https://www.benchmark.com/">https://www.benchmark.com/</a></p><i>eBoys: The First Inside Account of Venture Capitalists at Work</i> by Randall E. Stross <a href="https://www.amazon.com/eBoys-Inside-Account-Venture-Capitalists/dp/0812930959">https://www.amazon.com/eBoys-Inside-Account-Venture-Capitalists/dp/0812930959</a></p>Benchmark Part I on the Acquired Podcast <a href="https://www.acquired.fm/episodes/benchmark-capital">https://www.acquired.fm/episodes/benchmark-capital</a></p>Benchmark Part II on the Acquired Podcast <a href="https://www.acquired.fm/episodes/benchmark-part-ii-the-dinner">https://www.acquired.fm/episodes/benchmark-part-ii-the-dinner</a></p>Union Square Ventures <a href="https://www.usv.com/">https://www.usv.com/</a></p>Cerebras <a href="https://www.cerebras.net/">https://www.cerebras.net/</a></p>Eric Vishria on Twitter <a href="https://twitter.com/ericvishria">https://twitter.com/ericvishria</a></p> </p><strong>Connect with Boost VC</strong></p> </p>Boost VC Website <a href="https://www.boost.vc/">https://www.boost.vc/</a></p>Boost VC on Facebook <a href="https://www.facebook.com/boostvc/">https://www.facebook.com/boostvc/</a></p>Boost VC on Twitter <a href="https://twitter.com/BoostVC">https://twitter.com/BoostVC</a></p>Boost VC on Instagram <a href="https://www.instagram.com/boost_vc/">https://www.instagram.com/boost_vc/</a></p>

00:41:09

DeSci Ep # 7: How DeSci Bridges Academia and the Startup World—with Niklas Rindtorff of LabDAO

Many independently minded, young scientists are too ambitious for academia… But the startup world isn’t quite right for them either.</p> </p>How might decentralized science provide a space for these innovators to do their work?</p> </p>Niklas Rindtorff is the classical scientist behind <a href="https://www.labdao.xyz/">LabDAO</a>, an online home for inventors that builds open tools for scientific research. Niklas coauthored his first paper before the age of 20, and he has expertise in CRISPR and cancer research.</p> </p>On this episode of Boost VC, Niklas joins us to explain how classical science emerged after World War II and explore the problems with the NIH grant funding process.</p> </p>Niklas shares his open-access approach to consuming scientific media and describes how DeSci is experimenting with different ways to measures the importance of new science.</p> </p>Listen in to understand how decentralized science can serve as the bridge between research organizations and science startups, building an ecosystem for inventors who don’t fit into the nonprofit or for-profit world.</p> </p><strong>Topics Covered</strong></p> </p>How Niklas defines science</p><ul><li>Formal knowledge generation process</li><li>Fishing at edge of what is known</li></ul> </p>How World War II changed the way we do science</p><ul><li>Conflict won because of US sophisticated tech</li><li>NIH funding created class of full-time scientists</li><li>System doesn’t always maximize progress</li></ul> </p>How the importance of new science is determined</p><ul><li>Measured by citations vs. markets</li><li>DeSci experiments with different accounting</li></ul> </p>How Niklas consumes scientific media</p><ul><li>Used to use few free, open-access journals</li><li>Now leverage Twitter bookmarks, preprints</li></ul> </p>What LabDAO does for scientists</p><ul><li>Provide tools to work wherever they are</li><li>Current focus on computational biology</li></ul> </p>What inspired Niklas to build LabDAO</p><ul><li>Experience with inventions stuck in bureaucracy</li><li>Measure number of patients treated vs. citations</li></ul> </p>The age distribution of NIH grant recipients</p><ul><li>Ages with scientists who were first</li><li>No market discipline, don’t answer to public</li></ul> </p>How we might equalize the demographic of NIH winners</p><ul><li>Create more NIHs</li><li>Private funding agency with philanthropic match</li></ul> </p>How we might invest in a portfolio of science</p><ul><li>Charge higher fee to run research-oriented fund</li><li>Online collectives do research sponsorships</li></ul> </p>How LabDAO itself is funded</p><ul><li>Nonprofit governed by token</li><li>Private investors buy token for stake on projects</li></ul> </p>The relationship between academia and DeSci</p><ul><li>Connective tissue among existing organizations</li><li>Inventors who don’t fit in academia or startups</li></ul> </p>Niklas’ definition of success</p><ul><li>Strive toward personal values</li><li>Invent cool stuff</li></ul> </p><strong>Connect with Niklas RIndtorff</strong></p> </p>LabDAO <a href="https://www.labdao.xyz/">https://www.labdao.xyz/</a></p>LabDAO on Discord <a href="https://discord.com/invite/labdao">https://discord.com/invite/labdao</a></p>LabDAO on GitHub <a href="https://github.com/labdao">https://github.com/labdao</a></p>LabDAO on Snapshot <a href="https://snapshot.org/#/labdao.eth">https://snapshot.org/#/labdao.eth</a></p>LabDAO on Medium <a href="https://medium.com/@labdao">https://medium.com/@labdao</a></p>LabDAO on Twitter <a href="https://twitter.com/lab_dao">https://twitter.com/lab_dao</a></p>Niklas on Twitter <a href="https://twitter.com/niklas_tr">https://twitter.com/niklas_tr</a>  </p> </p><strong>Resources</strong></p> </p>Broad Institute <a href="https://www.broadinstitute.org/">https://www.broadinstitute.org/</a></p>‘Science the Endless Frontier’ 1945 Report to Congress <a href="https://www.nsf.gov/od/lpa/nsf50/vbush1945.htm">https://www.nsf.gov/od/lpa/nsf50/vbush1945.htm</a></p>National Institutes of Health <a href="https://www.nih.gov/">https://www.nih.gov/</a></p>Public Library of Science <a href="https://plos.org/">https://plos.org/</a></p>bioRxiv <a href="https://www.biorxiv.org/">https://www.biorxiv.org/</a></p>New Science <a href="https://newscience.org/">https://newscience.org/</a></p>VitaDAO <a href="https://www.vitadao.com/">https://www.vitadao.com/</a></p> </p><strong>Connect with Boost VC</strong></p> </p>Boost VC Website <a href="https://www.boost.vc/">https://www.boost.vc/</a></p>Boost VC on Facebook <a href="https://www.facebook.com/boostvc/">https://www.facebook.com/boostvc/</a></p>Boost VC on Twitter <a href="https://twitter.com/BoostVC">https://twitter.com/BoostVC</a></p>Boost VC on Instagram <a href="https://www.instagram.com/boost_vc/">https://www.instagram.com/boost_vc/</a></p>

00:38:07

DeSci Ep # 6: Commercializing Science for Climate Solutions—with George Church & Ben Lamm of Colossal

In academia, most scientists publish their ideas and stop there. But if we want our breakthroughs to benefit society, we have to take it a step further. </p> </p>So, what does it look like to commercialize scientific research? What mindset do academics need to work at the intersection of science and industry?</p> </p>Ben Lamm has a career of building successful deep tech businesses, and George Church has a career of commercializing academic science. </p> </p>Together, they are the cofounders of <a href="https://colossal.com/">Colossal</a>, a breakthrough bioscience and genetic engineering company that is pioneering animal de-extinction technology to restore lost ecosystems for a healthier planet. </p> </p>On this episode of Boost VC, Ben and George join us to explain how bringing back the woolly mammoth addresses climate change and explore their approach to the ethical concerns around de-extinction.</p> </p>They discuss the benefits of Colossal technology beyond Arctic rewilding, describing how their work helps endangered animals and promotes conservation.</p> </p>Listen in for Ben and George’s insight on commercializing science and learn how to get comfortable enough with risk to turn academic ideas into industry.</p> </p><strong>Topics Covered</strong></p> </p>How George defines science</p><ul><li>Predict and create new options for humanity</li><li>Goal to build better world</li></ul> </p>Why Ben & George are bringing back the woolly mammoth</p><ul><li>Restore previous ratio of grass to trees</li><li>Sequester carbon at rate only possible in Arctic</li></ul> </p>How Ben & George approach the ethical concerns re: de-extinction</p><ul><li>Believe in radical transparency</li><li>Learn from negative feedback, people who question</li></ul> </p>Why George works at the intersection of academia and industry</p><ul><li>Likes to work with curious young people</li><li>Exposure to diversity of ideas</li></ul> </p>Why Colossal needs government collaboration and support</p><ul><li>Several governments, Indigenous groups in Arctic</li><li>Climate change, biodiversity and species preservation</li></ul> </p>How woolly mammoths promote carbon removal</p><ul><li>Knock down trees so more grass can grow</li><li>Cold, Arctic grasslands sequester carbon particularly well</li></ul> </p>The benefits of Colossal technology beyond Arctic rewilding</p><ul><li>Eradicate EHV virus in elephants</li><li>Promote species conservation</li></ul> </p>How Ben & George think about commercializing science</p><ul><li>Go beyond publication to help society</li><li>Feedback from investors and academia</li></ul> </p>What makes Ben & George’s partnership work</p><ul><li>George’s lab provides idea from academic study</li><li>Ben figures out product-market fit and funding</li></ul> </p>George’s advice to academics on commercializing products</p><ul><li>Can’t be afraid of failure</li><li>Can come back from bankruptcy</li></ul> </p>How Ben & George think about taking big risks</p><ul><li>Ben believed grandmother saying he could do anything</li><li>Academic failures taught George he would survive</li></ul> </p>The impact Ben & George hope to make with Colossal</p><ul><li>Ex utero development, species preservation</li><li>Thousands of Arctic elephants to sequester carbon</li><li>Advancements in reading and writing of genomes</li></ul> </p>How Ben & George define success</p><ul><li>Benefit society, facilitate survival of species</li><li>Create things that are additive</li></ul> </p><strong>Connect with George Church & Ben Lamm</strong></p> </p>Colossal <a href="https://colossal.com/">https://colossal.com</a></p>Colossal on Twitter <a href="https://twitter.com/ItIsColossal">https://twitter.com/ItIsColossal</a></p>Colossal on Facebook <a href="https://www.facebook.com/itiscolossal/">https://www.facebook.com/itiscolossal/</a></p>Colossal on Instagram <a href="https://www.instagram.com/itiscolossal/">https://www.instagram.com/itiscolossal/</a></p>George on Twitter <a href="https://twitter.com/geochurch">https://twitter.com/geochurch</a></p>Ben on Twitter <a href="https://twitter.com/federallamm">https://twitter.com/federallamm</a></p> </p><strong>Resources</strong></p> </p>Citizen Science <a href="https://www.citizenscience.gov/">https://www.citizenscience.gov/#</a></p>Personal Genome Project <a href="https://www.personalgenomes.org/">https://www.personalgenomes.org/</a></p>How to Grow (Almost) Anything <a href="https://www.media.mit.edu/courses/htgaa/">https://www.media.mit.edu/courses/htgaa/</a></p>DIYbio <a href="https://diybio.org/">https://diybio.org/</a></p>Church Lab <a href="https://arep.med.harvard.edu/">https://arep.med.harvard.edu/</a></p>Hypergiant <a href="https://www.hypergiant.com/">https://www.hypergiant.com/</a></p>Pleistocene Park <a href="https://pleistocenepark.ru/">https://pleistocenepark.ru/</a></p>Chris Mason Author Talk <a href="https://mitpress.mit.edu/blog/author-talk-the-next-500-years-by-christopher-e-mason/">https://mitpress.mit.edu/blog/author-talk-the-next-500-years-by-christopher-e-mason/</a></p><i>Prehistoric Planet </i><a href="https://tv.apple.com/us/show/prehistoric-planet/umc.cmc.4lh4bmztauvkooqz400akxav">https://tv.apple.com/us/show/prehistoric-planet/umc.cmc.4lh4bmztauvkooqz400akxav</a></p> </p><strong>Connect with Boost VC</strong></p>Boost VC Website <a href="https://www.boost.vc/">https://www.boost.vc/</a></p>Boost VC on Facebook <a href="https://www.facebook.com/boostvc/">https://www.facebook.com/boostvc/</a></p>Boost VC on Twitter <a href="https://twitter.com/BoostVC">https://twitter.com/BoostVC</a></p>Boost VC on Instagram <a href="https://www.instagram.com/boost_vc/">https://www.instagram.com/boost_vc/</a></p>

00:56:57

DeSci Ep #5: An Investor’s Perspective on DeSci—with James Sinka of Orange DAO

Why invest in decentralized science?</p> </p>James Sinka is a classically trained chemist and materials engineer and DeSci investor at <a href="https://www.orangedao.xyz/">Orange DAO</a>, a fund for crypto projects supported by an alliance of Y Combinator alumni.</p> </p>On this episode of Boost VC, James joins us to discuss where he sees opportunities in DeSci, describing the benefit of publishing null results and how open science helps us get to the truth more quickly.</p> </p>James explains how the Orange Fund and Orange DAO work together to finance crypto projects and shares his advice to scientist-founders on generating your own luck through action.</p> </p>Listen in for James’ insight on the first use cases for decentralized science and learn how investing in DeSci can democratize access to research and help rebel scientist-entrepreneurs ship products in the real world!</p> </p><strong>Topics Covered</strong></p> </p>How James defines science</p><ul><li>Process to uncover truths about world</li><li>Not an institution of truth</li></ul> </p>What attracted James to DeSci</p><ul><li>Benefits of publishing null results</li><li>Less wasted science effort and money</li></ul> </p>How James got into crypto</p><ul><li>Exposed to Bitcoin in college</li><li>Offers financial freedom to bet on self</li></ul> </p>How Orange DAO works</p><ul><li>$50M fund for crypto projects</li><li>Y Combinator alum support efforts</li></ul> </p>James’ advice for founders</p><ul><li>Bias toward action</li><li>Be willing to be wrong</li></ul> </p>Where James sees opportunity in DeSci</p><ul><li>Free flowing access to information</li><li>Get to truth more quickly</li></ul> </p>What’s wrong with academic science now</p><ul><li>Research for prestige, not passion</li><li>Value determined by citation numbers</li></ul> </p>How the Alzheimer’s fraud happened</p><ul><li>Conflict of interest at NIH</li><li>No reverse accountability system</li></ul> </p>What inspires James to invest in DeSci</p><ul><li>Push boundaries of scientific research</li><li>Help scientists build real products</li></ul> </p>James’ take on the first use case for DeSci</p><ul><li>Data warehousing (null results)</li><li>New forms of publication open to all</li></ul> </p>James’ definition of success</p><ul><li>Time, space and resources</li><li>Ability to do what you love</li></ul> </p><strong>Connect with James Sinka</strong></p> </p>Orange DAO <a href="https://www.orangedao.xyz/">https://www.orangedao.xyz/</a></p>Orange DAO on Discord <a href="https://discord.com/invite/DVncb7UxGB">https://discord.com/invite/DVncb7UxGB</a></p>Orange DAO on Snapshot <a href="https://snapshot.org/#/orangedaoxyz.eth">https://snapshot.org/#/orangedaoxyz.eth</a></p>Orange DAO on Etherscan <a href="https://etherscan.io/token/0x1bBD79f1Ecb3f2cCC586A5E3A26eE1d1D2E1991f">https://etherscan.io/token/0x1bBD79f1Ecb3f2cCC586A5E3A26eE1d1D2E1991f</a></p>Orange DAO on OpenSea <a href="https://opensea.io/collection/alumni-gems">https://opensea.io/collection/alumni-gems</a></p>Orange DAO on Twitter <a href="https://twitter.com/OrangeDAOxyz">https://twitter.com/OrangeDAOxyz</a></p>James on Twitter <a href="https://twitter.com/jamessinka">https://twitter.com/jamessinka</a>  </p> </p><strong>Resources</strong></p> </p><i>Through the Wormhole</i> <a href="https://www.imdb.com/title/tt1513168/">https://www.imdb.com/title/tt1513168/</a></p>Y Combinator <a href="https://www.ycombinator.com/">https://www.ycombinator.com/</a></p>NEAR Protocol <a href="https://near.org/">https://near.org/</a></p>Algorand <a href="https://www.algorand.com/">https://www.algorand.com/</a></p>Blockchain Capital <a href="https://blockchain.capital/">https://blockchain.capital/</a></p>The Memo by Howard Marks <a href="https://link.chtbl.com/thememobyhowardmarks">https://link.chtbl.com/thememobyhowardmarks</a></p>Multicoin Capital <a href="https://multicoin.capital/">https://multicoin.capital/</a></p>Solana <a href="https://solana.com/">https://solana.com/</a></p>Exploring Decentralized Science with Balaji Srinivasan <a href="https://www.youtube.com/watch?v=xrcRI_hYDtQ">https://www.youtube.com/watch?v=xrcRI_hYDtQ</a></p>Naval <a href="https://nav.al/">https://nav.al/</a></p>Brian Armstrong <a href="https://twitter.com/brian_armstrong">https://twitter.com/brian_armstrong</a></p>Epsilon3 <a href="https://www.epsilon3.io/">https://www.epsilon3.io/</a></p>Benchling <a href="https://www.benchling.com/">https://www.benchling.com/</a></p>Amplitude <a href="https://amplitude.com/">https://amplitude.com/</a></p>Sci-Hub <a href="https://sci-hub.se/">https://sci-hub.se/</a></p>Patrick Joyce on the Boost VC Podcast <a href="https://www.boost.vc/bvc/2022/08/04/desci-ep-2-addressing-the-misalignment-of-incentives-in-science">https://www.boost.vc/bvc/2022/08/04/desci-ep-2-addressing-the-misalignment-of-incentives-in-science</a>   </p>DeSci Labs <a href="https://desci.com/">https://desci.com/</a></p> </p><strong>Connect with Boost VC</strong></p> </p>Boost VC Website <a href="https://www.boost.vc/">https://www.boost.vc/</a></p>Boost VC on Facebook <a href="https://www.facebook.com/boostvc/">https://www.facebook.com/boostvc/</a></p>Boost VC on Twitter <a href="https://twitter.com/BoostVC">https://twitter.com/BoostVC</a></p>Boost VC on Instagram <a href="https://www.instagram.com/boost_vc/">https://www.instagram.com/boost_vc/</a></p>

01:08:10

DeSci Ep #4: Decentralizing Drug Development—with Paul Kohlhaas & Tyler Golato of Molecule

Under the current centralized system, drug development happens in silos. </p> </p>Pharmaceutical companies don’t share information. Scientists run the same failed experiments over and over again. And the process of bringing a drug to market typically takes ten-plus years. </p> </p>But Paul Kohlhaas and Tyler Golato are building a new way to do drug development. A system that allows for collaboration and dramatically increases the speed of breakthroughs in healthcare. </p> </p>CEO Paul and CSO Tyler are the Cofounders of <a href="https://www.molecule.to/">Molecule</a>, a decentralized biotech protocol that establishes a Web3 marketplace for research-related intellectual property. </p> </p>On this episode of Boost VC, Paul and Tyler join us to explain how their personal experiences with the failures of healthcare inspired their interest in changing the system. </p> </p>They discuss Molecule's end-to-end ecosystem for bringing drugs to market, describing how their IP-NFT both protects innovation and makes it more open, sharable and collaborative. </p> </p>Listen in for insight on Eroom's Law and learn how open science leads to enormous efficiency gains in the drug development process.</p> </p><strong>Topics Covered</strong></p> </p>How Paul & Tyler define science</p><ul><li>Empirical discovery of knowledge</li><li>Progressive search for truth</li></ul> </p>What inspired Paul & Tyler’s interest in science</p><ul><li>Personal experience with failures of healthcare</li><li>Potential for DeSci to foster new behaviors</li></ul> </p>Paul & Tyler’s failed experiment with crowdfunding</p><ul><li>Tried to raise money for microdosing study</li><li>Partnership with University of Toronto</li></ul> </p>How Molecule has evolved since 2019</p><ul><li>Ecosystem for bringing drugs to market</li><li>IP-NFT framework for collaboration</li></ul> </p>How to make scientists more open to sharing</p><ul><li>Improve user experience</li><li>Streamline funding process</li></ul> </p>The power of Molecule’s IP-NFT framework</p><ul><li>Intellectual property rights held on chain</li><li>Collectively owned by patients</li></ul> </p>The value prop for open science</p><ul><li>Creates enormous efficiency gains</li><li>Makes drug development much cheaper</li></ul> </p>Jack Scannel’s naming of Eroom’s Law</p><ul><li>Technology to discover drugs improving</li><li>Yet drug discovery output in decline</li></ul> </p>The goals for DeSci over the next decade</p><ul><li>Extend quality of human health span</li><li>Make science self-sovereign, self-aware</li></ul> </p>How Paul & Tyler define success</p><ul><li>Remain true to values and vision for life</li><li>Net positive impact on every person</li></ul> </p><strong>Connect with Paul Kohlhaas & Tyler Golato</strong></p> </p>Molecule <a href="https://www.molecule.to/">https://www.molecule.to/</a></p>Molecule on GitHub <a href="https://github.com/moleculeprotocol">https://github.com/moleculeprotocol</a></p>Molecule on Discord <a href="https://discord.com/invite/uAGW7K4hQU">https://discord.com/invite/uAGW7K4hQU</a></p>Molecule on YouTube <a href="https://www.youtube.com/channel/UCWYW5ho3L_d0EO_a619E7RQ">https://www.youtube.com/channel/UCWYW5ho3L_d0EO_a619E7RQ</a></p>Molecule on LinkedIn <a href="https://www.linkedin.com/company/molecule-protocol">https://www.linkedin.com/company/molecule-protocol</a>  </p>Molecule on Twitter <a href="https://twitter.com/molecule_dao">https://twitter.com/molecule_dao</a></p>Paul on Twitter <a href="https://twitter.com/paulkhls">https://twitter.com/paulkhls</a></p>Tyler on Twitter <a href="https://twitter.com/GolatoTyler">https://twitter.com/GolatoTyler</a></p> </p><strong>Resources</strong></p> </p>Linum Labs <a href="https://www.linumlabs.com/">https://www.linumlabs.com/</a></p>Molecule’s Crowdfunding Experiment with the University of Toronto <a href="https://www.molecule.to/blog/psychedelics-on-the-blockchain">https://www.molecule.to/blog/psychedelics-on-the-blockchain</a></p>NIH Grants and Funding <a href="https://www.nih.gov/grants-funding">https://www.nih.gov/grants-funding</a></p>Simon de la Rouviere on Bonding Curves <a href="https://www.youtube.com/watch?v=-k4M6QAW2pM">https://www.youtube.com/watch?v=-k4M6QAW2pM</a></p>Jack Scannell on Eroom’s Law <a href="https://refoundable.com/research/life-after-erooms-law-interview-with-jack-scannell.html">https://refoundable.com/research/life-after-erooms-law-interview-with-jack-scannell.html</a></p>Meme Lordz <a href="https://memelordz.io/">https://memelordz.io/</a></p>North American Association of Technology Transfer <a href="http://aim.autm.net/">http://aim.autm.net/</a></p>Ray Kurzweil <a href="https://www.kurzweilai.net/">https://www.kurzweilai.net/</a></p>Peter Diamandis <a href="https://www.diamandis.com/">https://www.diamandis.com/</a></p>Abundance 360 <a href="https://www.abundance360.com/summit">https://www.abundance360.com/summit</a></p> </p><strong>Connect with Boost VC</strong></p> </p>Boost VC Website <a href="https://www.boost.vc/">https://www.boost.vc/</a></p>Boost VC on Facebook <a href="https://www.facebook.com/boostvc/">https://www.facebook.com/boostvc/</a></p>Boost VC on Twitter <a href="https://twitter.com/BoostVC">https://twitter.com/BoostVC</a></p>Boost VC on Instagram <a href="https://www.instagram.com/boost_vc/">https://www.instagram.com/boost_vc/</a></p>

00:54:51

DeSci Ep #3: Why Scientists Are the Unappreciated Creator Class—with Jocelynn Pearl of LabDAO

The internet has given content creators of all kinds a way to monetize their talents. Writers have Medium. Teachers and vloggers have YouTube. </p> </p>But scientists don’t have a platform to earn money for their research. </p> </p>That’s why Dr. Jocelynn Pearl calls scientists the ‘unappreciated creator class.’ And that’s why she’s working to further the DeSci movement, leveraging Web3 technology to enable breakthrough research through better incentives.</p> </p>A molecular and cellular biologist by training, Jocelynn serves as cofounder of <a href="https://www.labdao.xyz/">LabDAO</a>, a design marketplace for life science research, and host of <a href="https://rss.com/podcasts/ultrarare/">The UltraRare Podcast</a>, a show about the builders behind the decentralized science movement.</p> </p>On this episode of Boost VC, Jocelynn joins us to explain how DeSci solves for speed of translation and communicates science better than existing systems, exploring how the movement might specifically facilitate breakthroughs around rare disease.</p> </p>Jocelynn discusses how academia owns the best scientific minds without rewarding them appropriately and describes how DAOs offer alternatives to classic academic publishing and drug development.</p> </p>Listen in as Jocelynn makes the case that scientists are the unappreciated creator class and learn how access to the right advisors and capital can accelerate the decentralized science movement.</p> </p><strong>Topics Covered</strong></p> </p>How Jocelynn defines science</p><ul><li>Process of exploring unanswered questions</li><li>Conversation among people trained to be critical</li></ul> </p>How Jocelynn defines decentralized science</p><ul><li>Way of democratizing resources</li><li>Communicate science better than existing systems</li></ul> </p>What inspired Jocelynn’s interest in DeSci</p><ul><li>Centralization of research inhibits progress</li><li>Solve for speed of translation, cost reduction</li></ul> </p>How DeSci might facilitate breakthroughs in rare disease</p><ul><li>Explore drug development through DAOs</li><li>Communication of collective knowledge</li></ul> </p>Leveraging DeSci to incentivize scientific research</p><ul><li>Change academic publishing through tokenization</li><li>Allow patient group to co-own drug development</li></ul> </p>Why Jocelynn sees scientists as the unappreciated creator class</p><ul><li>Writers have Medium, vloggers have YouTube</li><li>No platform for scientists to monetize content</li></ul> </p>What needs to change for scientists to be appreciated creators</p><ul><li>Activists like Seemay Chou who encourage sharing</li><li>Alternative model to academic publishing</li></ul> </p>How academia owns the best minds (without rewarding them)</p><ul><li>Earn $30K/year working full-time in PhD program</li><li>Does form you as scientist and provides network</li></ul> </p>How CROs address the lab space shortage</p><ul><li>Stands for contract research organization</li><li>Farm out research can’t perform in-house</li></ul> </p>The challenges of establishing decentralized science</p><ul><li>Traditional academia and publishing will fight back</li><li>Much work required to override existing system</li></ul> </p>What's stopping the DeSci space from accelerating faster</p><ul><li>Struggles to bring in advising and capital</li><li>Working on projects outside day jobs</li></ul> </p>Jocelynn’s definition of success </p><ul><li>Lasting change in scientific ecosystem</li><li>Pivot how progress happens </li></ul> </p><strong>Connect with Jocelynn Pearl</strong></p> </p>Jocelynn’s Website <a href="https://www.jocelynnpearl.com/">https://www.jocelynnpearl.com/</a></p>LabDAO <a href="https://www.labdao.xyz/">https://www.labdao.xyz/</a></p>LabDAO on Twitter <a href="https://twitter.com/lab_dao">https://twitter.com/lab_dao</a></p>LabDAO on GitHub <a href="https://github.com/labdao">https://github.com/labdao</a>  </p>LabDAO on Discord <a href="https://discord.com/invite/labdao">https://discord.com/invite/labdao</a></p>UltraRare Podcast <a href="https://rss.com/podcasts/ultrarare/">https://rss.com/podcasts/ultrarare/</a></p> </p><strong>Resources</strong></p> </p>A Guide to Decentralized Biotech <a href="https://future.com/a-guide-to-decentralized-biotech/">https://future.com/a-guide-to-decentralized-biotech/</a></p>The DeSci Wiki <a href="https://www.jocelynnpearl.com/">https://www.jocelynnpearl.com/</a></p>Molecule Protocol <a href="https://www.molecule.to/">https://www.molecule.to/</a></p>Ben Hills <a href="https://twitter.com/0xboodle">https://twitter.com/0xboodle</a></p>Vibe Bio <a href="https://www.vibebio.com/">https://www.vibebio.com/</a></p>Experiment.com <a href="https://experiment.com/">https://experiment.com/</a></p>Arcadia Science <a href="https://www.arcadia.science/">https://www.arcadia.science/</a></p>Invisible College <a href="https://www.invisiblecollege.xyz/">https://www.invisiblecollege.xyz/</a></p>Charles River Laboratories <a href="https://www.criver.com/">https://www.criver.com/</a></p>Cameron & Tyler Winklevoss on Boost VC EP102 <a href="https://podbay.fm/p/the-boost-vc-podcast/e/1606903200">https://podbay.fm/p/the-boost-vc-podcast/e/1606903200</a></p>Manhattan Project <a href="https://www.history.com/topics/world-war-ii/the-manhattan-project">https://www.history.com/topics/world-war-ii/the-manhattan-project</a></p>Thiel Fellowship <a href="http://www.thielfellowship.org/">http://www.thielfellowship.org/</a></p> </p><strong>Connect with Boost VC</strong></p> </p>Boost VC Website <a href="https://www.boost.vc/">https://www.boost.vc/</a></p>Boost VC on Facebook <a href="https://www.facebook.com/boostvc/">https://www.facebook.com/boostvc/</a></p>Boost VC on Twitter <a href="https://twitter.com/BoostVC">https://twitter.com/BoostVC</a></p>Boost VC on Instagram <a href="https://www.instagram.com/boost_vc/">https://www.instagram.com/boost_vc/</a></p> </p>

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